CKDNapp publications

Kotsis F. , Bächle H. Altenbuchinger M., Dönitz J., Njipouombe N.Y.A., Meiselbach H., Kosch R., Salloch S., Bratan T., Zacharias H.U., Schultheiss U.T.
Expectation of clinical decision support systems: a survey study among nephrologist end-users
BMC Medical Informatics and Decision Making Volume 23, article number 239, (2023)

Zacharias H.U., Altenbuchinger M., Schultheiss U.T. et al.
A Predictive Model for Progression of CKD to Kidney Failure Based on Routine Laboratory Tests
American Journal of Kidney Diseases, 79(2): 217-230.e1 (2022)

Schrod S., Schäfer A., Solbrig S., Lohmayer R., Gronwald W., Oefner P. J., Beißbarth T., Spang R., Zacharias H.U., Altenbuchinger M.
BITES: Balanced Individual Treatment Effect for Survival data
Bioinformatics (Oxford Academic), (2022)

Guebila M.B., Weighill D., Lopez-Ramos C.M., Burkholz R., Pop R.T., Palepu K., Shapoval M., Fagny M., Schlauch D., Glass K., Altenbuchinger M. et al.
An online notebook resource for reproducible inference, analysis and publication of gene regulatory networks
Nature Methods (2022)

Lotta L.A., Pietzner M., Stewart I.D., Wittemans L.B.L., Li C., Bonelli R., Raffler J. et al.
A cross-platform approach identifies genetic regulators of human metabolism and health
Nature Genetics (2021)

Pietzner M., Stewart I.D., Raffler J. et al.
Plasma metabolites to profile pathways in noncommunicable disease multimorbidity
Nature Genetics (2021)

Zacharias H.U., Hertel J., Johar H. et al.
A metabolome-wide association study in the general population reveals decreased levels of serum laurylcarnitine in people with depression
Molecular Psychiatry volume 26, pages 7372–7383 (2021)

Schultheiss U.T., Kosch R., Kotsis F. et al.
Chronic Kidney Disease Cohort Studies: A Guide to Metabolome Analyses
Metabolites 11(7), 460; (2021)

Winitzki D., Zacharias H.U., Nadal J. et al.
Educational Attainment Is Associated With Kidney and Cardiovascular Outcomes in the German CKD (GCKD) Cohort
Kidney International Reports VOLUME 7, ISSUE 5, P1004-1015, MAY (2022)

Cheng Y., Li Y., Scherer N., Grundner-Culemann F., Lehtimäki T., Mishra B.H., Raitakari O.T., Nauck M., Eckardt K., Sekula P., Schultheiss U.T. et al.
Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study
PloS Genetics April 6 (2022)

Li Y., Cheng Y., Consolato F., Schiano G., Chong M.R., Pietzner M., Nguyen N.G.H., Scherer N., Biggs M.L., Kleber M.E., Haug S., Göçmen B., Pigeyre M., Sekula P., Steinbrenner I., Schlosser P., Joseph CB., Brody J.A., Grams M.E., Hayward C., Schultheiss U.T. et al.
Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases
Journal of Clinical Investigation Insight (2022)

Steinbrenner I., Sekula P., Kotsis F. et al.
`Association of osteopontin with kidney function and kidney failure in chronic kidney disease patients: the GCKD study
Nephrology Dialysis Transplantation (2021)

Steinbrenner I., Schultheiss U.T., Kotsis F. et al.
Urine Metabolite Levels, Adverse Kidney Outcomes, and Mortality in CKD Patients: A Metabolome-wide Association Study
American Journal of Kidney Diseases (2021)

Kotsis F., Schultheiss U.T. et al.
Self-Reported Medication Use and Urinary Drug Metabolites in the German Chronic Kidney Disease (GCKD) Study
Journal of the American Society of Nephrology (JASN) (2021)

Pammer L.M, Lamina C., Schultheiss U.T., Kotsis F. et al.
Association of the metabolic syndrome with mortality and major adverse cardiac events: A large chronic kidney disease cohort
Journal Internal Medicine (JIM) (2021)

Schultheiss U.T., Peggy S.
The Promise of Metabolomics in Decelerating CKD Progression in Children
Clinical Journal of the American Society of Nephrology (CJASN) (2021)

Bonk S., Hertel J., Zacharias H.U. et al.
Vitamin D moderates the interaction between 5‑HTTLPR and childhood abuse in depressive disorders
Scientific reports (2020)

Schultheiss U.T. et al.
Thyroid function, renal events and mortality in chronic kidney disease patients: the German Chronic Kidney Disease study
Clinical Kidney Journal, sfaa052 (2020)

Sekula P., Tin A., Schultheiss U.T. et al.
Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease
Sci Rep 10, 10018 (2020)

Pietzner M., Wheeler E., Carrasco-Zanini J., Raffler J. et al.
Genetic architecture of host proteins interacting with SARS-CoV-2
Preprint at bioRxiv (2020)

Altenbuchinger M., Zacharias H.U., Solbrig S. et al.
A multi-source data integration approach reveals novel associations between metabolites and renal outcomes in the German Chronic Kidney Disease study
Sci Rep 9, 13954 (2019)

Zacharias H.U., Altenbuchinger M., Schultheiss U.T. et al.
A novel metabolic signature to predict the requirement of dialysis or renal transplantation in patients with chronic kidney disease
J. Proteome Res. 2019, 18, 4, 1796-1805 (2019)

Schlosser P., Li Y., Sekula P., Raffler J. et al.
Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans
Nat Genet 52, 167–176 (2020)